Portfolio

Overview

For 20 years, our strategy has been consistent – identify and invest in the most promising healthcare ventures led by remarkable and inspired management teams.

We do more than just invest in innovative companies. We establish a partnership with our portfolio companies. The relationship continues beyond the final exit. Members of the SV team are actively involved in the development and/or growth of each portfolio company. We always serve as active board members. We collaborate with management teams to minimize risk and maximize the value of the business, using cash in the most effective way and participate in exit discussions for the benefit of management and investors.

Here’s how we contribute:

Board of Directors

  • Provide leadership on the company’s board of directors and various sub‐committees
  • Support and guide the management team from entry to exit
  • Recruit additional key hires to senior management and independent board members

Corporate Growth

  • Assist in the procurement of supplemental debt and equity capital
  • Support, shape and review the business plan, budgets and strategic direction
  • Identify corporate, product and technology acquisition targets, and partnerships

Healthcare Expertise

  • Provide access to an international network of leading experts and key opinion leaders with specific domain knowledge
  • Convey understanding of consumer behavior as well as physician and patient needs
  • Impart knowledge of legislative initiatives and regulatory approval processes

Deal Structure, Business Plan and Exit Strategies

  • Assist with pragmatic milestone-based business plans to promote focus and ROI
  • Establish contingency plans (e.g., identify merger opportunities for growth)
  • Identify likely corporate investors/acquirers and build toward a successful exit
  • Grow industry leading companies that are bought, not sold

Biotechnology

We invest in novel science, and we seek breakthroughs – truly innovative medicines, platform technologies, and diagnostics that have the potential to change the practice of medicine.

Current Investments

Bicycle Therapeutics
Calchan Holdings
Catabasis Pharmaceuticals
Deciphera Pharmaceuticals
ErVaxx Limited
Good Start Genetics, Inc
Juvaris BioTherapeutics
Kalvista Pharmaceuticals
Karus Therapeutics
Kesios Therapeutics Limited
NKT Therapeutics, Inc
Oxagen Limited/Atopix Therapeutics Limited
PanOptica
Pionyr Immunotherapeutics
Pulmocide
Sitryx Therapeutics Limited
Sutro Biopharma, Inc.
Thesan Pharmaceuticals
TopiVert
Vantia Pharmaceuticals
VHSquared

Previous Investments

Achillion Pharmaceuticals
Aderis Pharmaceuticals
Affibody
Affinium Pharmaceuticals
Alantos Pharmaceuticals
Allocure
Allos Therapeutics
Antiva (Vantia Spin-Out)
Auxilium Pharmaceuticals
Avant Immunotherapeutics, Inc.
Avera Pharmaceuticals
Axys Pharmaceuticals
Celldex/Lorantis
Cellzome
Cerebrus
Cognis
Convergence Pharmaceuticals
Cyterix Pharmaceuticals
Cytomed
Delenex Therapeutics
Dynogen Pharmaceuticals
ESBATech
EUSA Pharma
Eyetech Pharmaceuticals
Geltex Pharmaceuticals
GlycoFi
Gyros AB
Ikano Therapeutics
Imagen Biotech
Incyte Pharmaceuticals
Ingenium
Itero Biopharmaceuticals
Kinetix Pharmaceuticals
KuDOS Pharmaceuticals
LeukoSite
Link Medicine
Logical Therapeutics
Lux Biosciences
Metris Therapeutics
Micromet
Mpex Pharmaceuticals
NeurogesX
Neurotech
Nigra plc
Oncoethix
Ophthotech
Orchid Chemicals
PowderMed
Quantum Dot
Rempex Pharmaceuticals
RespiVert
Rinat Neuroscience
Sapphire Therapeutics
Shire Pharmaceuticals
Solexa
Strides Arcolab
Third Wave Technologies
Triangle Pharmaceuticals
Trine Pharmaceuticals
Vanguard Medica (Vernalis)
Versicor
X2-Pharma

Medical Devices

We target compelling teams and differentiated technologies that address major, unmet clinical needs – disrupting cost, relieving the symptomatic burdens of illness, and improving quality of life.

Current Investments

Endotronix
Entellus
Ocular Therapeutix
ReShape
Soffio Medical
Spinal Kinetics
TransEnterix
ValenTx
Ximedica

Previous Investments

AqueSys
Argonaut Technologies
Cardiac Support Systems
CardioMind
Cellutions
Cerebral Vascular Applications
CHF Solutions
Concentric Medical
Confluent Surgical
Eunoe
Euro Dentalversand Holding
General Surgical Innovations
Genosis
Halscion
Insulet
Leica Microsystems
LenSx Lasers, Inc
LipoSonix
MedNova
Micromass
MicroMed
MindFrame
NeoVista
Nexan
NovaLign
Orthovita
Pelton & Crane
Sadra Medical
Sirona Dental Systems

Healthcare Services and Digital Health

Healthcare services and digital health are transformational – they’re at the center of healthcare reform and cost containment. We seek growth equity opportunities in new services, delivery tools and healthcare IT.

Previous Investments

Accelecare Holdings
Allegiance Hospice Group
AllianceCare
Aptiv Solutions
BioCore Holdings (BioClinica)
Broadlane
Cadent Technologies
Celerion
Coral Therapeutics
CoreLab Partners
CRI Worldwide
EasyChem
eMed Technologies
Euro Dentalversand
Expand Sante
Healogics
Heritage Health Systems
Homecare Homebase
IHG Holdings
ISG Holdings
JC Nationwide
MDeverywhere
OMS Foundations
Patient Care
Phase Forward
Physicians Dialysis
Quick Study Radiol
Ricerca Biosciences
Socios Mayores en Salud
Synarc
The Corner Pharmacy
TLC Vision
Vintage BioMed
Vitalize Consulting Solutions