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Houman Ashrafian

Scientific Advisor

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Since joining SV in 2016, Houman has co-founded seven currently active SV companies; Sitryx, Enara Bio, TRexBio, Alchemab, Catamaran Bio, Mestag and Dualitas and serves on the board of five of these companies; Enara Bio, Alchemab, Catamaran Bio, Mestag and Dualitas. He also serves onthe boards of Therini, Imbria, Quell and Prilenia.

Previously, Houman co-founded the services company Cardiac Report in 2003, as well as Heart Metabolics in 2008. Heart Metabolics successfully repositioned perhexiline, as a treatment for hypertrophic cardiomyopathy and heart failure. Perhexiline is now in advanced clinical trials and has orphan drug designation. He went on to become Vice President and head of the Clinical Science Group at UCB Pharma.

Outside of SV, following completion of his cardiology training, Houman was appointed as an Honorary Consultant Cardiologist in 2011 at the John Radcliffe Hospital in Oxford. He is Visiting Professor and Head of Experimental Therapeutics at the University of Oxford. Additionally, Houman is co-founder and Chairman of Weatherden, a boutique clinical development company.

Academic credentials

Undergraduate degree, University of Cambridge; BM BCh, DPhil, University of Oxford.

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