Houman Ashrafian

Managing Partner

Houman joined SV in 2016 as a Venture Partner, was promoted to Partner in 2017 and became a Managing Partner in 2018.

He has founded four SV companies, attracting strategic investment into three within 12 months at valuation uplifts.  He is currently CEO of Ervaxx and TRexBio.

Houman serves on the Dementia Discovery Fund (DDF) Investment Committee.

Read more about Houman’s work as a Venture Partner

Prior experience
Houman co-founded the services company Cardiac Report in 2003, as well as Heart Metabolics in 2008. Heart Metabolics successfully repositioned perhexiline, as a treatment for hypertrophic cardiomyopathy and heart failure. Perhexiline is now in advanced clinical trials and has orphan drug designation. He went on to become Vice President and head of the Clinical Science Group at UCB. Pharma before becoming an SV Venture Partner.

Academic credentials
Undergraduate degree, University of Cambridge; BM BCh, DPhil, University of Oxford

Outside of SV
Following completion of his cardiology training, Houman was appointed as an Honorary Consultant Cardiologist in 2011 at the John Radcliffe Hospital in Oxford. He is Visiting Professor and head of Experimental Therapeutics at the University of Oxford.

He is cofounder and Chairman of Weatherden, a boutique clinical development company, and cofounder of Cinpovium.

Investment Team


Sector Administrator
Catherine Ahern


Current Portfolio